In this paper, titled ‘Cellular contractile forces are non-mechanosensitive’, we studied the time evolution of cellular contractile forces and show that they are generated by time-dependent actomyosin contractile displacements that are independent of the environment’s rigidity. Consequently, contractile forces are non-mechanosensitive. We further show that the force-generating displacements are directly related to the evolution of the actomyosin network near the adhesions.
You can find the Biorxiv version here: https://www.biorxiv.org/content/10.1101/733303v2.full.pdf