Welcome to the  Wolfenson Lab website. We are located at the Rappaport Faculty of Medicine of the Technion – Israel Institute of Technology.

We study fundamental aspects of cellular interactions with the extracellular matrix. We are particularly interested in the ways by which the mechanical features of the extracellular matrix affect cellular functions under normal and disease conditions, including their effects on cancer progression.

Our aim is to identify new avenues to attack cancer, with the premise that the mechanobiological cellular pathways (the adhesion and cytoskeletal systems) are vulnerable to treatment since they have much less redundancy compared to biochemical pathways.

Please visit our research page for more details on our lab’s projects

  • Fibroblast stained for alpha-catenin (green) & vinculin (red)
  • Fibroblasts stained for F-actin & DAPI
  • Epithelial cells stained for alpha-catenin (green) & DAPI (white)
  • Fibroblast plated on fibronectin micro-patterns (magenta), stained for paxillin (green) & F-actin (red)
  • Fibroblast stained for paxillin (green), F-actin (magenta) & DAPI (blue)
  • Fibroblast stained for paxillin (green) & F-actin (red)